Pharmaceutical Companies Manufacturing

The pharmaceutical marketplace has changed dramatically over the last few years as pharmaceutical companies are moving from centralized, internal production to single-source providers or Contract Manufacturing Organizations (CMO).

The principal reason behind this evolution in the landscape is simple, to cut costs, increase capacity and reduce time-to-market. Beyond these obvious criteria, there are numerous other reasons why pharmaceutical companies are relying heavily on the growing CMO market.

Whereas CMOs once produced primary packaging they now offer a multitude of services from design and discovery to final packaging.

Outsourcing to a CMO allows the pharmaceutical company to add technical resources without increasing its overhead costs. The result of this is that the pharmaceutical company does not need to invest in expanding its staff and manufacturing facilities, to add new varieties of medicines into its product lines.

Pharmaceutical companies can now concentrate on core products regarding R&D and production and leave its secondary and tertiary products to the CMO.

CMOs of Increasing Importance to Pharmaceutical Companies 

What is a CMO?

The term CMO can refer to a multitude of different companies including Contract Packaging Organization, Contract Pharmaceutical Manufacturer. However, in recent years CMOs have been more or less classified into two types of organizations:

API Contract Manufacturer (Active Pharmaceutical Ingredient)

These are companies that manufacture a substance(s) that are used as a component of a finished drug.

FDF Contract Manufacturer (Finished Dosage Form)

These are companies that provide a drug product for administration to a patient without the need for substantial further manufacturing and often in its final packaged form. The CMO market is currently divided almost equally between API manufacturers and FDF manufacturers.

Within FDF contract manufacturing, solid dose compounds currently dominate the market. However, future growth is likely to be driven by injectables dose manufacturing primarily due to increased focus on complex disease areas and the growing trend of self-administration.

A Growing Market

Regarding market growth and potential future growth, the CMO channel is a force to reckon with.  

For North America, Europe, and Japan in the last three years, the CMO market grew at close to three times the rate of the pharmaceutical market: 8% versus 3%.

(It is important to note that the 3% growth is for the pharmaceutical market as a whole, top Pharmaceutical companies have grown significantly faster at a rate on average of over 11%. It is also important to note that most large pharmaceutical companies have divisions operating as CMO)

Over the next five years, the CMO market is expected to continue to grow at an annual rate of 6% to 9%, with annual revenues currently valued at between 25-30 billion dollars. This growth will be further fueled by new opportunities within the generic drug market.

Challenges for the CMO

Although the CMO seems to be poised to become a major player in the pharmaceutical marketplace several challenges await.

Acquisitions

The trend is already apparent as 2015 saw a glut of companies and manufacturing facilities being bought and sold.

Current Clients

Smaller pharmaceutical companies use the services of CMOs significantly more than large pharmaceutical companies.  The challenge lies in that the growth opportunities are a lot smaller.

Low Capital Costs

With lower capital costs many pharmaceutical companies are rethinking the CMO route for moving back to traditional centralized production.

The Future of CMOs

As with any part of the pharmaceutical landscape, the role of the CMO will follow a predictable route. Larger ones will absorb the smaller CMOs, and the large CMOs will come forward to be the only players to be able to support the large Pharmaceutical and Biopharmaceutical companies.

New channels will open within the generic pharmaceutical marketplace fostering further growth for the large CMO.


GlobalVision is the leading developer of proofreading technologies for the FDF Contract Manufacturer market. All our quality control solutions meet FDA 21 CFR Part 11 / EMA Annex 11 requirements.

For more information on GlobalVision and the Quality Control Platform for CMOs, please visit: globalvision.co or email: info@globalvision.co


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Happy man with automated proofreading process

Creating content for public consumption can be a stressful job. Think about the person that has to write the copy for the back of a Cheerios box. Millions of people will read the back of that cereal box every morning and any typos would be terrible for the brand and the consumers’ confidence in the product. Now imagine someone reading the back of an allergy medication. What if a typo occurs in the dosage section? This has happened and it costs companies millions of dollars in recalls.

How to proofread a document

Ideally, every company needs a diff checker like your old high-school English teacher. But this just won’t happen and businesses need to turn to other more practical solutions. Enter proofreading software, which will catch every mistake and not even breathe coffee breath on you.

Why automated proofreading software is better than your  teacher

Saves you embarrassment – Ever raise your hand because you thought you knew where the comma went in the sentence written on the board? It was a trick question anyway; The sentence needed a semi-colon. You looked silly and ruined your chances at junior prom with the literature whiz. Proofreading software will scan your printed material, compare it to the approved master and will identify that missing semi-colon for you. Hopefully, your senior year was kinder to you.

Software saves you time – Getting a paper back from a teacher can take a while. They generally wait to grade everything one day while watching reruns of Downton Abbey. Proofreading can inspect multiple documents in a matter of seconds.

English teachers aren’t that great at art – While an English teacher can tell you the difference between a dangling participle and a prepositional phrase, few are professionals at those “spot the differences” puzzles. Proofreader software can not only proofread documents and inspect text, but it can also inspect artworkbarcodes and even Braille. Since it inspects pixel-by-pixel, artwork is no problem at all. So, if a logo is messed up, a barcode is missing a line, or a beloved tiger is missing a stripe, proofreading software will point it out and you can make the fix before it is too late.

You love the feedback – How often was your first draft the exact same as your final draft? The stakes were not too high back in high school. Only one person read your paper and put a letter grade on it and that was the end of it. In a corporate setting, mistakes can cost you your job and the company millions of dollars in recalls. Never will you be so happy to have a mistake pointed out to you. It will save your company money and that means job security.

Thank goodness for English teachers. Without them and their strict ways who knows where the language would be today. However, when it comes to packages, labels, or printed documents, a proofreading software solution is the only way to go.


Learn how GlobalVision has helped Consumer Goods companies of all sizes and protected brands’ reputation by preventing common errors on packaging 

For more information, please visit globalvision.co or contact info@globalvision.co


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Monitor screen filled with all kinds of inspection work
 
 

Ghent (Belgium), March 16, 2016 – Esko has completely updated its software solutions and relaunched them under the umbrella brand name “Esko Software Platform”. It’s the next version of the well-known portfolio of integrated software solutions for design, prepress, workflow automation, color management and supply chain collaboration used for packaging, labels, displays and signs.

The Esko Software Platform is enhanced with new capabilities and delivers a unique user experience. The full range of innovations and integrations of Esko Software Platform will be demonstrated for the first time at the upcoming drupa 2016, scheduled for May 31 through June 10 in Düsseldorf.


Highlights of the Drupa release of the Esko Software Platform include:

  • More software modules made available as Software as a Service (SaaS) and subscriptions
  • Improved 3D support, especially when viewing objects in WebCenter and on mobile devices
  • A new Content Management module for WebCenter
  • ArtPro+, a totally new platform-independent native PDF prepress editor
  • New tools and libraries for multi-part POP design in ArtiosCAD 16
  • Planogram interface for Store Visualizer 16
  • New set of automated quality assurance tools in Automation Engine
  • Esko hardware integration in the workflow (Automation Engine Device View)
  • Improved user experience across all applications

A Platform for Quality Control

“Esko has embedded technologies from our partner GlobalVision and from our subsidiary Enfocus to eliminate time-consuming manual checks,” Zwaenepoel states. “Automated quality checking tools allow our customers to process more jobs with the same people and with fewer errors”. This innovation offers peace of mind and addresses the lack of skilled operators many companies are facing.”


GlobalVision quality control solution tools are embedded in Automation Engine 16. Features now available from the automated workflow include a spell checker and automatic checking of barcodes and Braille against an approved profile. The quality check runs as a background process and results in an annotated and viewable design file for Automation Engine, WebCenter and in ArtPro+. This enables fast, systematic revision of all detected errors.

Please visit the Esko Software Platform for more information on what’s new within Esko.

Request a free trial for GlobalVision Packaging Quality Control Solution.

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What does GlobalVision do?

GlobalVision’s mission is to build software that standardizes quality approvals for product packaging and critical content. Our goal is to eliminate errors and automate inspections so companies can release products with confidence. Helping Businesses Bring Confidence to Quality Control. Learn more about GlobalVision.

What is GlobalVision Quality Control?

Automate Quality Inspections for Fast and Consistent Results. Speed up the proofreading process while improving the accuracy of your work by running digital checks with GlobalVision’s automated quality control tools. Learn more about Automated Quality Control.